The activities of the network of 13 projects in the Member States and 4 projects in the Candidate States are co-ordinated by the Co-ordination Centre (Cytological Institute of the Bavarian Cancer Society), and are grouped in 4 thematic clusters, as follows:

• PART 1: Quality Assurance and Quality Control
  Cluster Leader: Professor Ulrich Schenck
  The development and improvement of innovative quality assurance and quality control tools and the evaluation of their impact for improving quality assurance strategies on cervical screening through the external review of laboratory and individual performance by an independent agency.

• PART 2: Monitoring, Epidemiology and Evaluation of Cervical Screening
  Cluster Leader: Dr Ahti Antilla
  Continuation of the long-term monitoring and epidemiological evaluation of the cervical screening in several European regions, with the objective of establishing realistic results outcome indicators, and to estimate costs-benefits and to minimise the adverse effects.

• PART 3: New Technologies in Cervical Screening
  Cluster Leader: Dr Marc Arbyn
  Investigation of technological innovation. Continuous incorporation of technical innovation will allow to improve the quality of the European cervical screening. The results will help to determine the diagnostic parameters of new technologies in cervical screening in terms of sensitivity, specificity, predictive values and reproducibility.

• PART 4: Teamwork and Information Dissemination via Internet
  Cluster Leader: Professor Ulrich Schenck
  Improvement of WEB FORUM, the communication platform for teamwork, discussions and dissemination of the network results. Implementation of multilingual User Interfaces and of an efficient search engine.